Fastp is an ultra-fast integrated tool for FASTQ data preprocessing and quality control. It can complete multiple tasks in a single run, including: automatic identification and removal of adapter sequences, filtering of low-quality bases, length filtering, filtering of low-complexity sequences, base correction (for paired-end data), polyG/polyX tail trimming, etc. Fastp supports batch processing of multiple FASTQ files and provides detailed HTML format quality control reports. Compared with traditional multi-tool serial workflows (such as Trimmomatic + FastQC), Fastp significantly improves the running speed while ensuring the processing quality, and is one of the preferred tools for RNA-seq data preprocessing.