Cross-species embryonic transcriptomic datasets were integrated to establish a standardized quantitative evaluation system for evolutionary research.
Core Findings
Developed a derivative index to quantitatively measure embryonic differentiation degrees
Identified conserved core genes governing embryonic morphogenesis
Clarified the evolutionary rule that molecular differentiation drives embryonic phenotypic divergence in animals
Publication Info: Published in Frontiers series journals (IF = 5.8)
Research Progress
Establishment of a Novel Quantitative Index for Embryonic Evolution; Comparative Transcriptomics Decodes Developmental Differentiation Mechanisms of Deuterostomes
👤 Yang Dong’s Group
📅 十一月 02, 2021
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Summary:The research pioneered a quantitative index for embryonic phenotypic differentiation. Transcriptomic data from chordates and echinoderms were compared to dissect the molecular drivers of early embryonic morphological evolution. The paper was published in the Frontiers series journals (Impact Factor: 5.8).